Image analysis engineer Institut Pasteur/Cell Death and Epithelial Homeostasis group (permanent[...]

Image Analysis Engineer - Institut Pasteur/Cell Death and Epithelial Homeostasis Group (Permanent Position)Our research group (Cell Death and Epithelial Homeostasis) located in Institut Pasteur (Paris, France) in the department of Developmental and Stem Cell Biology is seeking an engineer in image analysis to join our group through a permanent position, ideally to start in September 2024.Our group is interested in the fine tuning of cell death in epithelial context using mostly Drosophila as a model system. We use a wide range of live imaging techniques and develop new tools (including live sensors and optogenetics) to quantitatively dissect the feedback fine tuning of cell death. Our group has been developing various pipelines (z reconstruction, segmentation and tracking, automatic recognition of cellular events through deep learning, force inference…) and is looking for stable support that will help us to:Develop new pipelines for image analysis mostly for 4D movies (PIV, segmentation, tracking, force inference, features extractions…)Maintain and update pipelines previously developed by the groupSurvey newly published methods and adapt them for our needsAssist in the quantitative analysis of our datasetsHelp maintain and share our pipelines with a large public through the development of user-friendly codes and visual interfacesTrain the members of the unit in good practices in data management, code writing, and data sharing.We are looking for a candidate with good coding knowledge (mostly Python, but also Matlab and Java), good theoretical knowledge of fluorescent live imaging, expertise in machine learning applied to image analysis, a real interest in collaborative work, and the capacity to work on several projects in parallel with good listening skills.The applicant will join a dynamic and supportive group that promotes a healthy work-life balance, with members coming from various backgrounds, and located in a collegial and vibrant department. The application will also get close interactions with the growing community of image analysts on campus.If you are interested, please send a single PDF document with CV, cover letter, Github/Gitlab link, and reference contact to [email protected] (with the subject “engineer position”).The official job advertisement can be found in the following link:Matamoro-Vidal, A., Cumming, T., Davidovic, A., and Levayer, R. Patterned apoptosis modulates local growth and tissue shape in a fast-growing epithelium. Current Biology 34, 1-13, https://doi.org/10.1016/j.cub.2023.12.031 (2024).Villars, A., Letort, G., Valon, L. & Levayer, R. DeXtrusion: automatic recognition of cell extrusion through machine learning in vivo. Development 150 (13), https://doi.org/10.1242/dev.201747 (2023).Villars, A., Matamoro-Vidal, A., Levillayer, F. & Levayer, R. Microtubule disassembly by caspases is an important rate-limiting step of cell extrusion. Nat Commun 13, 3632, https://doi.org/10.1038/s41467-022-31266-8 (2022). #J-18808-Ljbffr